Promethazine blocks dopamine, alpha and histamine receptors to reduce nausea and vomiting, and produce sedation.
This combination medication is used to treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). Promethazine is an antihistamine that relieves watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. Phenylephrine is a decongestant that relieves stuffy nose symptoms. Codeine is a narcotic cough suppressant (antitussive) that affects a [...]
Phenergan tablets and elixir contain the active ingredient promethazine, which is a type of medicine called a sedating antihistamine. It works by preventing the actions of histamine.
Promethazine is a phenothiazine in the same drug class as chlorpromazine (Thorazine) and trifluoperazine (Stelazine). However, unlike the other drugs in this class, promethazine is not used as an anti-psychotic. It used as an anti-histamine, sedative, and antiemetic (anti-nausea). The body releases histamine during several types of allergic reactions. When histamine binds to its receptors [...]
